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Toxicology Defined

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Off-site Toxicology Links, User Submitted

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Sun Jul 5

• International Neurotoxicolog y Association (INA) Conference examines effects of exposure to pesticides | Health | Jerusalem Post: The realization that chemicals can damage the central nervous system is not very old, so there are not many specialists with extensive knowledge of both neurology and toxicology. Eighty of these interdisciplin ary experts from 16 countries, including the US, Israel, Nigeria, Japan, Estonia, Poland, Spain, Italy, the UK, India and France met last month at the Kibbutz Ma'aleh Hahamisha Guest House outside Jerusalem to discuss the latest discoveries in the field. Few of the foreign participants had ever been here. The five-day biennial meeting of the International Neurotoxicolog y Association (INA) focused on Gene-Environme nt Interactions in Neurotoxicolog y...

Sat Jul 4

• International Register of Drug Information Services
• Current Awareness in Clinical Toxicology
• National Poisons Information Service

Fri Jul 3

• Ambient: Toxicology Module
• New and Strange: Canadian HIV vaccine ready for human tests

Thu Jul 2

• EXTOXNET Global Search
• Drug analysis a multistep process - CNN.com

Wed Jul 1

• Glyphosate-bas ed herbicides are toxic and endocrine disruptors in human cell lines: (..) We exposed human liver HepG2 cells, a well known model to study xenobiotic toxicity, to four different formulations and to glyphosate, which is usually tested alone in chronic in vivo regulatory studies. We measured cytotoxicity with three assays (Alamar Blue®, MTT, ToxiLight®), plus genotoxicity (comet assay), anti-estrogeni c (on ER?, ER?) and anti-androgeni c effects (on AR) using gene reporter tests. We also checked androgen to estrogen conversion by aromatase activity and mRNA. All parameters were disrupted at sub-agricultur al doses with all formulations within 24 h. These effects were more dependent on the formulation than on the glyphosate concentration. First, we observed a human cell endocrine disruption from 0.5 ppm on the androgen receptor in MDA-MB453-kb2 cells for the most active formulation (R400),(..)

Tue Jun 30

• ScienceDirect - Journal of Pharmacologica l and Toxicological Methods, Volume 59, Issue 3, Pages 121-180 (May-June 2009): The online version of Journal of Pharmacologica l and Toxicological Methods on ScienceDirect, the world's leading platform for high quality peer-reviewed full-text publications in science, technology and health.

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Off-site Toxicology Research Links

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